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In article number 1701316, by Gisbert Schneider and co‐workers, a novel peptide descriptor enables the rational design of peptides based on their topological hydrophobic distribution. Applying this descriptor, a computational method generates an innovative peptide inspired by a natural template. This peptide is then trialed and optimized for its ability to disrupt bacterial cells by forming ordered,...
Specific interactions of peptides with lipid membranes are essential for cellular communication and constitute a central aspect of the innate host defense against pathogens. A computational method for generating innovative membrane‐pore‐forming peptides inspired by natural templates is presented. Peptide representation in terms of sequence‐ and topology‐dependent hydrophobic moments is introduced...
This paper deals with the control design for large cooling loops with large and time varying delays and measured disturbances. A control oriented model is presented and a two-degree-of-freedom control strategy is introduced. The feedforward part of the controller is designed using inputoutput linearization techniques. The control performance with respect to trajectory tracking and disturbance rejection...
Force regulation is an important topic in pick-and-place applications. To this end, a novel control concept for a setup consisting of two serially and co-linearly mounted axes is proposed. The position trajectory of the larger axis is tracked by a standard PD-controller. The feedback-law for the second and smaller axis mounted on the slide of the larger one is designed as an impedance control. A particular...
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