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It is hypothesized that CD4+CD25+FoxP3+ regulatory T cells (Tregs) can prevent destruction of pancreatic islets protecting from type 1 diabetes (DM1).Here we present results of one year follow-up of 12 DM1 children treated with autologous expanded ex vivo Tregs. Patients received either a single or double Tregs infusion up to the total dose of 30×106/kg.No severe adverse effects were observed. The...
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