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Recent work in biomolecule‐metal–organic framework (MOF) composites has proven to be an effective strategy for the protection of proteins. However, for other biomacromolecules such as nucleic acids, the encapsulation into nano MOFs and the related characterizations are in their infancy. Herein, encapsulation of a complete gene‐set in zeolitic imidazolate framework‐8 (ZIF‐8) MOFs and cellular expression...
Gene therapy utilizing non‐viral delivery systems still lags behind its viral counterpart despite being the safer method. In article number 1902268, Ravi Shukla and co‐workers explore the potential of metal–organic frameworks (MOFs) for gene delivery. The most fundamental aspect of DNA, its ability to translate into proteins, is investigated to determine the suitability of MOFs as delivery agents...
Motile metal−organic frameworks (MOFs) are potential candidates to serve as small‐scale robotic platforms for applications in environmental remediation, targeted drug delivery, or nanosurgery. Here, magnetic helical microstructures coated with a kind of zinc‐based MOF, zeolitic imidazole framework‐8 (ZIF‐8), with biocompatibility characteristics and pH‐responsive features, are successfully fabricated...
Metal–organic frameworks (MOFs) have been recently used as building blocks in micro‐ and nanoswimmers; in article number 1901592, Josep Puigmartí‐Luis and co‐workers present 3D soft‐based MOF microrobots that can swim along pre‐designed tracks, achieving both single‐cell targeting in a cell‐culture media and controlled delivery of cargo payloads.
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