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Although novel molecular targeted drugs have been recognized as an effective therapy for non-small cell lung cancer (NSCLC) harboring epidermal growth factor receptor (EGFR) activating mutations, their efficacy fails to meet the expectation due to the acquired resistance in tumors. Up-regulation of the anti-apoptotic protein Survivin was shown to contribute to the resistance to EGFR tyrosine kinase...
Carbon nanotube (CNT)–organic polymer hybrids have important potential applications in the immobilization of therapeutic biomolecules. Recently developed CNT–organic polymer composites require the use of organic solvents for their preparation and have limited polymer functionalization. To address these limitations, multi-walled CNT (MWCNT)–chitosan nanoparticle (CS NP) hybrids have been synthesized...
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