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The degradation of collagen fibrils and elastic fibers in 21 casesof acute aortic dissection (AD) was ultrastructurally and immunohistochemicall investigated; and the expression of the catabolic matrix metalloproteinases (MMPs)-1, -2, -3, and -9 and their inhibitors, the tissue inhibitors of matrix metalloproteinase (TIIMPs)-1 and -2, was studied. The features of the entry site of the dissection (ES;...
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