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In article number 1703207, Jianjun Chen, Zongqiang Cui, and co‐workers develop an intranasal nanovaccine which provides protection against homo‐ and heterosubtypic influenza. The 3M 2e‐rHF nanovaccine is constructed by displaying three‐sequential repeats of the influenza conserved antigen M2e on the self‐assembling recombinant human heavy chain ferritin (rHF) cage. Intranasal vaccination with 3M2e‐rHF...
Cross‐protective and non‐invasively administered vaccines are attractive and highly desired for the control of influenza. Self‐assembling nanotechnology provides an opportunity for the development of vaccines with superior performance. In this study, an intranasal nanovaccine is developed targeting the conserved ectodomain of influenza matrix protein 2(M2e). 3‐sequential repeats of M2e (3M2e) is presented...
Superparamagnetic iron oxide nanoparticles (SPIONs) have been extensively used as bioimaging contrast agents, heating sources for tumor therapy, and carriers for controlled drug delivery and release to target organs and tissues. These applications require elaborate tuning of the physical and magnetic properties of the SPIONs. The authors present here a search‐coil‐based method to characterize these...
The nonlinear magnetic response of SPIONs to magnetic fields induces harmonic signals that contain information of these nanoparticles. In article number 1604135, Jian‐Ping Wang and co‐workers, report using the phase lag and harmonic ratios in the SPIONs to analyze the saturation magnetization, average hydrodynamic size, the dominating relaxation processes of SPIONs, and the distinction between single‐...
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