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Mossy fiber sprouting (MFS) is the main characteristic of temporal lobe epilepsy (TLE), which is highly correlated with the frequencies of recurrent seizures as well as degrees of severity of TLE. A recent MRI technique, referred to as diffusion spectrum imaging (DSI), can resolve crossing fibers and investigate the intravoxel heterogeneity of water molecular diffusion. Being able to achieve higher...
Mapping complex crossing fibers using diffusion MRI techniques requires adequate angular precision and accuracy. Beyond diffusion tensor imaging (DTI), high angular resolution sampling schemes such as diffusion spectrum imaging (DSI) and q-ball imaging (QBI) were proposed to resolve crossing fibers. These schemes require hundreds of data approximately five to ten times more than DTI, offsetting their...
Diffusion MRI is a technique that can probe diffusivity of water molecules in brain structure non-invasively and so that it presents complex neuronal orientation by discrete ribbons. In the study, a new tractography algorithm for high angular resolution diffusion imaging was developed to connect the discrete neural orientations and to extract sophisticated neuronal connectivity in human brain. By...
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