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Chromosomes are condensed in all forms of life. SMC-based condensins are the key mediators in this process, but their molecular mechanisms remain elusive. Two different condensin complexes have been identified in prokaryotic organisms: MukB–MukE–MukF and SMC–ScpA–ScpB. This review focuses on comparison between the two machineries based on structural, biochemical and other related information in the...
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