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Over the last decade tissue engineering has emerged as a powerful alternative to regenerate lost tissues owing to trauma or tumor. Evidence shows that Schwann cell containing scaffolds have improved performance in vivo as compared to scaffolds that depend on cellularization post implantation. However, owing to limited supply of cells from the patients themselves, several approaches have been taken...
Identification of the most successful strategy for applications in tissue engineering is often confusing, with a wide variety of options and variables available, that can fit into an ideal graft or scaffold. The complexity of the problem is multifold in application of grafts for regeneration of peripheral nerve injuries, with many variables that affect the regeneration process and thereby the success...
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