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Introduction IgE-dependent activation of mast cells and basophils through the high-affinity IgE receptor (FcɛR1) is involved in the pathogenesis of allergen-induced immune responsiveness in atopic disease including bronchial asthma. Materials and methods We genotyped 650 children for allelic determinants at two polymorphic sites, −109T/C and E237G, in the FcɛR1β gene by SNP-IT™ assays using the...
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