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BackgroundA few studies have examined the durability of transcranial magnetic stimulation (TMS) antidepressant benefit once patients remitted. This study examined the long‐term durability of clinical benefit from TMS using a protocol‐specified TMS taper and either continuation pharmacotherapy or naturalistic follow‐up.
MethodsPatients were remitters from an acute double‐blind sham‐controlled trial of TMS (n = 18), or from an open‐label extension in patients who did not respond to the acute trial (n = 43). Long‐term durability of TMS acute effect was examined in remitters over a 12‐week follow‐up. Relapse, defined as 24‐item Hamilton Depression Rating Scale (HDRS‐24) ≥20, was the primary outcome...
Objective: To assess the efficacy of increasing the number of fast left repetitive transcranial magnetic stimulations (rTMS) (10 Hz @ 120% of motor threshold (MT) over the left dorsolateral prefrontal cortex (DLPFC)) needed to achieve remission in treatment‐resistant depression (TRD). And, to determine if patients who do not remit to fast left will remit using slow right rTMS (1 Hz @ 120% MT over...
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