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BackgroundNeuromyelitis optica (NMO) is an inflammatory disease involving predominantly the spinal cord and optic nerves. Whether patients with NMO have a loss in white or grey matter (GM) volumes remains to be determined.
MethodsThirty patients with NMO, 30 healthy subjects matched for age and gender, 21 patients with multiple sclerosis (MS) and 20 patients with a clinically isolated syndrome (CIS)...
“Disease activity free” in relapsing-remitting multiple sclerosis (RRMS) is a new concept introduced by the results of the AFFIRM study. Our objective was to analyze the clinical and radiological efficacy of natalizumab treatment in actual clinical practice and compare it with the post hoc analysis of the AFFIRM study. All patients with RRMS who began treatment with natalizumab at our two French MS...
The detection of Multiple Sclerosis (MS) lesions in Magnetic Resonance (MR) images remains an important issue in medical image processing. Diagnostic criteria for MS based on brain MRI concern mainly dissemination in space and time. In this context, this paper describes a novel region- based approach to automatically count the number of MS lesions present in a set of MR images. Given a set of candidate...
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