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Complement‐mediated allograft injury, elicited by donor‐specific HLA antibodies (DSA), is a defining pathophysiological characteristic of allograft damage. We aimed to study DSA‐induced complement activation as a diagnostic marker of antibody‐mediated rejection (AMR) and a risk stratification tool for graft loss in the context of lung transplantation (LT). We identified 38 DSA‐positive patients whose...
Cytomegalovirus (CMV) is one of the most problematic pathogens in the immunocompromised host after solid organ and stem cell transplantation, increasing morbidity and mortality risk, and graft loss. In order to accurately quantify immunity to CMV, both antibody titers and measures of virus-specific T cell activation are needed. While CMV-specific IgG and IgM antibodies are routinely tested in the...
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