Search results for: Dae‐Hyun Ko

Items from 1 to 18 out of 18 results

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Trends in category and grade for therapeutic plasma exchange in the latest guideline on therapeutic apheresis by the American Society for Apheresis: Hurdles in pursuing evidence‐based medicine

Han Joo Kim, Yousun Chung, Hyungsuk Kim, Sang‐Hyun Hwang, more

Background and Objectives The Writing Committee of American Society for Apheresis released the ninth edition of guidelines for therapeutic apheresis in 2023. Categories have been a part of the guidelines since the first edition, and the grading system was introduced in the fifth edition, with updates in every new edition. In this study, we investigated the category and grade change trends through...

article

Time–temperature indicators versus temperature indicators for transfusion practice: Application in the real hospital setting

Mikyoung Park, Mina Hur, Hanah Kim, Kyungmi Oh, more

Vox Sanguinis > 117 > 3 > 354 - 360

Background and Objectives Temperature indicators (TIs) are used to monitor the surface temperature of red blood cell (RBC) units. We compared the utility of a newly developed time–temperature indicator (TTI) prototype, Freshzone TTI (FZTTI) (Freshzone, Seoul, South Korea) and two US Food and Drug Administration–approved TIs, Safe‐T‐Vue 10 (STV10; Temptime Corporation, Morris Plains, NJ) and Blood...

article

Evaluation of safety of using incompatible plasma for therapeutic plasma exchange during shortage of AB plasma

John Jeongseok Yang, Kyong‐Suk Ryu, Jin Seok Kim, Yousun Chung, more

Journal of Clinical Apheresis > 36 > 4 > 628 - 633

Background Criteria for selection of FFP blood type has not been clearly established and use of group AB plasma is preferred by numerous transplantation protocols. Aims This study assesses the safety and efficacy of alternative group A or B plasma in ABO incompatible solid organ transplantation. Materials & Methods Alternative use of group A or B plasma (incompatible plasma) was inevitable...

article

Risk management strategy for reducing therapeutic plasma exchange‐related allergic reactions

Taegeun Lee, John Jeongseok Yang, Sihwan Kim, Hye‐jin Lee, more

Allergy > 75 > 4 > 962 - 965

article

ABO‐incompatible kidney transplantation can be successfully conducted by monitoring IgM isoagglutinin titers during desensitization

Hyungsuk Kim, Wonho Choe, Sung Shin, Young Hoon Kim, more

Transfusion > 60 > 3 > 598 - 606

BACKGROUND Recent advances in desensitization techniques and immunosuppressive therapy have led to improved outcomes after ABO‐incompatible (ABO‐i) kidney transplantation (KT). However, questions remain unanswered, particularly regarding which type of ABO isoagglutinin—immunoglobulin M (IgM) or immunoglobulin M (IgG)—is significantly involved in antibody‐mediated rejection (AMR). STUDY DESIGN AND...

article

Application of next-generation sequencing to detect variants of drug-resistant Mycobacterium tuberculosis: genotype–phenotype correlation

Dae-Hyun Ko, Eun Jin Lee, Su-Kyung Lee, Han-Sung Kim, more

Annals of Clinical Microbiology and Antimicrobials > 2019 > 18 > 1 > 1-8

Background Drug resistance in Mycobacterium tuberculosis (MTB) is a major health issue worldwide. Recently, next-generation sequencing (NGS) technology has begun to be used to detect resistance genes of MTB. We aimed to assess the clinical usefulness of Ion S5 NGS TB research panel for detecting MTB resistance in Korean tuberculosis patients. Methods Mycobacterium tuberculosis with various drug...

article

Performance of the Dimension TAC assay and comparison of multiple platforms for the measurement of tacrolimus

Eun‐Jung Cho, Dae‐Hyun Ko, Woochang Lee, Sail Chun, more

Journal of Clinical Laboratory Analysis > 32 > 4 > n/a - n/a

Background Therapeutic monitoring of tacrolimus is essential for reducing organ rejection and adverse effects. The measurement of tacrolimus in whole blood is taken by many automated platforms. We evaluated the analytical performance of the Dimension TAC assay, which is an upgraded reagent from the previous Dimension TACR assay. Methods The evaluations involved determination of precision, linearity,...

article

Effect of creatinine and cystatin C measurement variations on calculated estimated glomerular filtration rate variations and the theoretical impact on kidney disease stage classification: A retrospective study

Dae-Hyun Ko, Sung Woo Lee, Jungwon Hyun, Hyun Soo Kim, more

Clinica Chimica Acta > 2018 > 477 > C > 13-17

The estimated glomerular filtration rate (eGFR) is an important parameter in the management of patients with kidney diseases, yet eGFR quality goals are lacking. We examined the uncertainties in eGFR determinations and assessed their impact on patient classifications, aiming to set eGFR quality goals.Adult patients undergoing creatinine concentration assessments at our hospital, between June 2014...

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Corrigendum to “The 99th percentile values of six cardiac troponin assays established for a reference population using strict selection criteria” [Clin. Chim. Acta 464 (2017) 1–5]

Dae-Hyun Ko, Tae-Dong Jeong, Eun-Jung Cho, Jinsook Lim, more

Clinica Chimica Acta > 2017 > 468 > C > 32

article

The 99th percentile values of six cardiac troponin assays established for a reference population using strict selection criteria

Dae-Hyun Ko, Tae-Dong Jeong, Eun-Jung Cho, Jinsook Lim, more

Clinica Chimica Acta > 2017 > 464 > C > 1-5

Since the 99th percentile reference limit for cardiac troponin (Tn) can vary depending on the reference population, Sandoval et al. published systematic selection criteria. In this study, these systematic criteria were applied for the first time to obtain the 99th percentile reference limits for 6 Tn tests.The reference population was selected in accordance with the systematic criteria, and reference...

article

Method evaluation of pepsinogen I/II assay based on chemiluminescent immunoassays and comparison with other test methods

Eun-Jung Cho, Hyun-Ki Kim, Tae-Dong Jeong, Dae-Hyun Ko, more

Clinica Chimica Acta > 2016 > 452 > Complete > 149-154

Serum pepsinogen (PG) I and the PG I/PG II ratio have been used for atrophic gastritis (AG) diagnosis for decades. Low levels of PG I and/or PG I/PG II are closely related to AG and predict the risk of gastric cancer. We evaluated the performance of the chemiluminescent immunoassay-based Architect Pepsinogen I/II assay.The evaluation consisted of determination of the precision, linearity, limit of...

article

A novel quantitative evaluation method for quality control results

Won-Ki Min, Dae-Hyun Ko, Eun Jung Cho, Tae-Dong Jeong, more

Clinica Chimica Acta > 2015 > 451 > PB > 175-179

Quality control (QC) procedures using stable control materials are important for preventing systematic errors (SEs). While the current QC methods assess QC results semi-quantitatively, we designed a novel quantitative QC procedure (QQCP).QC results were expressed as Z-scores to analyze results quantitatively. The decision values were accumulated up to 30, with three decision values per run, and were...

article

Novel GALT variations and mutation spectrum in the Korean population with decreased galactose-1-phosphate uridyltransferase activity

Rihwa Choi, Kyoung Il Jo, Dae-Hyun Ko, Dong Hwan Lee, more

BMC Medical Genetics > 2014 > 15 > 1 > 1-8

Background Classic galactosemia (OMIM #230400) is an autosomal recessive metabolic disorder caused by a deficiency of the galactose-1-phosphate uridyltransferase (GALT, EC2.7.7.12) protein due to mutations in the GALT gene. The aim of this study was to provide a comprehensive and updated mutation spectrum of GALT in a Korean population. Methods Thirteen unrelated patients screened positive for galactosemia...

article

Native ETV6 deletions accompanied by ETV6‐RUNX1 rearrangements are associated with a favourable prognosis in childhood acute lymphoblastic leukaemia: a candidate for prognostic marker

Dae‐Hyun Ko, Yongbum Jeon, Hyoung Jin Kang, Kyung Duk Park, more

British Journal of Haematology > 155 > 4 > 530 - 533

article

Newborn screening for galactosemia by a second-tier multiplex enzyme assay using UPLC-MS/MS in dried blood spots

Dae-Hyun Ko, Sun-Hee Jun, Kyoung Un Park, Sang Hoon Song, more

Journal of Inherited Metabolic Disease > 2011 > 34 > 2 > 409-414

Galactosemia is one of the most important inherited metabolic disorders detected by newborn screening tests. Abnormal results during screening should be confirmed by enzyme activity assays. Recently, we developed a multiplex enzyme assay for galactosemia in erythrocytes using ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). In this study, we proposed a second-tier multiplex...

article

Molecular and biochemical characterization of the GALT gene in Korean patients with galactose-1-phosphate uridyltransferase deficiency

Dae-Hyun Ko, Ho Eun Chang, Sang Hoon Song, Kyoung Un Park, more

Clinica Chimica Acta > 2010 > 411 > 19-20 > 1506-1510

Three different types of galactosemia have been described, and the most common form occurs due to a deficiency in the galactose-1-phosphate uridyltransferase (GALT) enzyme activity.To investigate the molecular defects of the GALT gene, PCR-direct sequencing was performed with genomic DNA from 18 Korean patients with reduced GALT activity.Of the 18 patients tested, 13 (72.2%) had previously reported...

article

Homozygous deletion of CDKN2A (p16, p14) and CDKN2B (p15) genes is a poor prognostic factor in adult but not in childhood B-lineage acute lymphoblastic leukemia: a comparative deletion and hypermethylation study

Miyoung Kim, Seon-Hee Yim, Nam-Sun Cho, Seong-Ho Kang, more

Cancer Genetics and Cytogenetics > 2009 > 195 > 1 > 59-65

The biological behavior of childhood B-lineage acute lymphoblastic leukemia (B-ALL) is different from that of adults. We performed a comprehensive analysis of the deletion and the methylation profile of CDKN2A (hereafter identified separately as p16 and p14, for the different proteins encoded) and CDKN2B (hereafter p15) in 91 newly diagnosed B-ALL patients (61 children, 30 adults). The prognostic...

article

168-P: Discrepancy of HLA typing results of unrelated stem cell donors between registry typing and confirmatory typing

Hye Yoon Chung, Dae-Hyun Ko, Young Mi Lim, Bok Youn Han, more

Human Immunology > 2009 > 70 > Supplement 1 > S96

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