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The aim of this study was to characterize early hepatic lipid changes in an experimental model of liver fibrosis using proton ( 1 H) magnetic resonance spectroscopy (MRS) at high magnetic field in vivo.Liver fibrosis was induced in 12 Sprague-Dawley rats by twice-weekly carbon tetrachloride (CCl 4 ) administration up to 4 weeks. Eight normal rats were used as controls. Single-voxel...
Hepatic ischemia/reperfusion injury (IRI) occurs during certain hepatobiliary surgeries, hemorrhagic shock, and veno-occlusive disease. Biochemical changes caused by hepatic IRI lead to hepatocellular remodeling, including cellular regeneration or irreversible apoptosis. This study aims to characterize and monitor the metabolic changes in hepatic IRI using proton magnetic resonance spectroscopy (...
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