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Key Points Surgical intervention including bullectomy, lung volume reduction surgery (LVRS) and lung transplantation can be considered in a select group of chronic obstructive pulmonary disease (COPD) patients. Bullectomy may result in improvement of some of the indices of respiratory function and dyspnoea with a gradual worsening over the years. Surgical LVRS...
In COPD patients, hyperinflation impairs cardiac function. We examined whether lung deflation improves oxygen pulse, a surrogate marker of stroke volume.In 129 NETT patients with cardiopulmonary exercise testing (CPET) and arterial blood gases (ABG substudy), hyperinflation was assessed with residual volume to total lung capacity ratio (RV/TLC), and cardiac function with oxygen pulse (O 2 ...
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