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Botulinum and tetanus neurotoxins are structurally and functionally related 150kDa proteins that are potent inhibitors of neuroexocytosis. Botulinum neurotoxin associates with non-toxic proteins to form complexes of various sizes. The botulinum neurotoxin and non-toxic protein genes are clustered in a DNA segment called the botulinum locus. This locus is probably located on a mobile or degenerate...
A microbiological study was made of 100 strains ofFusobacterium necrophorumisolated from hepatic abscesses in bovine and ovine herds. Differences between the biological activity and ribotypes within the twoF. necrophorumsubspecies were studied. Conventional methods identified 89 isolates asF. necrophorumsubsp.necrophorumand 11 asF. necrophorumsubsp.funduliforme. For ribotyping, 50 strains (35F.n.subsp...
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