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Dopamine (DA) is a central monoamine neurotransmitter involved in many physiological and pathological processes. A longstanding yet largely unmet goal is to measure DA changes reliably and specifically with high spatiotemporal precision, particularly in animals executing complex behaviors. Here, we report the development of genetically encoded GPCR-activation-based-DA (GRABDA) sensors that enable...
The Weather Research and Forecasting model was used to test the sensitivity of Typhoon Haiyan (2013) to the use of a cumulus parameterization scheme, specifically the revised Kain–Fritsch (rKF) scheme, at high horizontal resolutions with grid spacing varying from 9 to 2 km. The rKF scheme simulated the typhoon in best agreement with the observation compared with other schemes, but some fundamental...
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