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Purpose The purpose of the study was to assess the impact of age on the pharmacokinetics of immunosuppressive drugs. Methods One hundred and ten renal transplant recipients, including 12 elderly patients over 60 years of age, 57 middle-aged patients between 40 and 59 years and 41 young adult patients 20 to 39 years of age were studied. To evaluate dose-adjusted pharmacokinetics and cytochrome P450...
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