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The dual-band recording of the local-field potential (LFP, 0.1–200 Hz) and the spike potential (SP, 200 Hz–10 kHz) is important for physiological studies at the cellular level. Recent study shows that the LFP signal plays important roles in modulating many profound cellular mechanisms. Although various bio-signal acquisition circuits have been reported over the years, few designs are applicable to...
In a cell recording system, characteristics of the cell and microelectrode array (MEA) interface impose challenging requirements on the design of front-end amplifier with regard to input-referred noise, linearity, dynamic range (DR), input impedance, pitch size and differential electrode offset (DEO) cancellation. Previous front-end amplifier designs for cell recording demonstrated 2~7 ??Vrms input...
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