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Background.This study uses wrist actigraphy to assess the effects of 24-hr transdermal nicotine replacement on the sleep and daytime activity of smokers during smoking cessation.Methods.Seventy-one subjects grouped as light (n= 23), moderate (n= 24), or heavy (n= 24) smokers were randomly assigned to placebo or 11, 22, or 44 mg/day doses of transdermal nicotine for 1 week of intensive inpatient treatment...
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