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Autophagy is a highly conserved cellular degradative pathway that includes several tightly regulated steps, evolving from the initial formation of phagophores to autophagosomes, whose fusion with lysosomes results in the final structures of degradation, autolysosomes. Ectopic P-Granules Autophagy Protein 5 Homolog encoded by EPG5 is a key autophagy regulator in multicellular organisms. Recessive EPG5...
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