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We have used NMR experiments to explore the binding of selected glycans and glycomimetics to the SARS CoV‐2 spike glycoprotein (S‐protein) and to its receptor binding domain (RBD). STD NMR experiments confirm the binding of sialoglycans to the S‐protein of the prototypic Wuhan strain virus and yield dissociation constants in the millimolar range. The absence of STD effects for sialoglycans in the...
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