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We have used NMR experiments to explore the binding of selected glycans and glycomimetics to the SARS CoV‐2 spike glycoprotein (S‐protein) and to its receptor binding domain (RBD). STD NMR experiments confirm the binding of sialoglycans to the S‐protein of the prototypic Wuhan strain virus and yield dissociation constants in the millimolar range. The absence of STD effects for sialoglycans in the...
Hidradenitis Suppurativa (HS) is a chronic, recurrent, inflammatory, follicular skin disease whose pathology is complex and not fully understood. The objective of this study was to elucidate the role of IL‐17A in moderate‐to‐severe HS. Transcriptomic and histological analyses were conducted on ex vivo HS (n = 19; lesional and non‐lesional) and healthy control (n = 8) skin biopsies. Further, a Phase...