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Tea polyphenols have inhibitive effects for carcinogenesis. A reporter system controlled by hTERT promoter was constructed to evaluate the effects of tea polyphenols, (−)-epigallocatechin-3-gallate (EGCG) and (−)-epigallocatechin (EGC) on the repression of hTERT transcription. The hTERT promoter activity was selectively repressed by 20–40μM EGCG and EGC in a dose- and time-dependent manner. Real-time...
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