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Graphene and other 2D materials, such as molybdenum disulfide, have been increasingly used in electronics, composites, and biomedicine. In particular, MoS2 and graphene hybrids have attracted a great interest for applications in the biomedical research, therefore stimulating a pertinent investigation on their safety in immune cells like macrophages, which commonly engulf these materials. In this study,...
The cover, inspired by a famous album cover by Pink Floyd, represents the transformation of the “dark” undetected signal side of graphene into a visible signal, thanks to a specific functionalization with ZnS‐doped AgInS2 nanocrystals, allowing its tracking on the complex mix of human peripheral blood mononuclear cells at the single cell level, as presented in article number 2000123, by Davide Bedognetti,...
Considering the potential exposure to graphene, the most investigated nanomaterial, the assessment of the impact on human health has become an urgent need. The deep understanding of nanomaterial safety is today possible by high‐throughput single‐cell technologies. Single‐cell mass cytometry (cytometry by time‐of flight, CyTOF) shows an unparalleled ability to phenotypically and functionally profile...
In the growing area of nanomedicine, graphene-based materials (GBMs) are some of the most recent explored nanomaterials. For the majority of GBM applications in nanomedicine, the immune system plays a fundamental role. It is necessary to well understand the complexity of the interactions between GBMs, the immune cells, and the immune components and how they could be of advantage for novel effective...
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