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Samples of 39 canine mammary gland tumours (MGTs) were examined immunohistochemically for oestrogen receptor (ER-α), Bcl-2 protein and Ki67 antigen, and by TUNEL assay for apoptosis. ER-α was expressed by 80% (31/39) of the tumours, including all of the 15 benign tumours and 67% (16/42) of the malignant tumours. ER-α expression was greater in the benign than in the malignant tumours (P<0.01). Bcl-2...
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