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Connective tissue growth factor (CTGF) has been reported to play an important role in mediating the profibrotic effects of transforming growth factor-β (TGF-β) in various renal diseases. To elucidate the role of CTGF in renal tubular epithelial-myofibroblast transdifferentiation, we examined the expression of α-smooth muscle actin (α-SMA), vimentin, tenascin-C, and collagen IV expression upon the...
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