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JPH203 has been developed as an anticancer drug that inhibits L‐type amino acid transporter 1‐mediated essential amino acid uptake into tumor cells. This study sought to elucidate which drug transporters may be involved in JPH203 hepatic elimination, and to estimate human hepatic clearance. In Sprague–Dawley rats, JPH203 total body clearance approached blood flow rate. JPH203 biotransformation via...
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