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Neurotensin (NT) receptors in pancreatic and other neuroendocrine tumors are promising targets for imaging and therapeutic purposes. Here, we report on the effect of distinct changes in the peptide chain on catabolism in vitro for five radiolabeled [ 99m Tc] neurotensin analogues having high affinity for neurotensin receptors. Substitution of NT(1-7) by (NαHis)Ac-the Tc-binding moiety-combined...
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