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This study tested the ability of A0001 (α‐tocopheryl quinone; EPI‐A0001), a potent antioxidant, to improve in vitro measures, glucose metabolism, and neurological function in Friedreich ataxia. We used an in vitro study of protection from cell toxicity followed by a double‐blind, randomized, placebo‐controlled trial of 2 doses of A0001 in 31 adults with Friedreich ataxia. The primary clinical trial...
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