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BackgroundAdipose afferent reflex (AAR) contributes to sympathetic activation and hypertension. Paraventricular nucleus (PVN) plays an important role in AAR and sympathetic outflow. The aim of the present study was to determine whether PVN mediates AAR response to insulin in a rat model of insulin resistance (IR).
MethodsMale Sprague‐Dawley rats were randomly divided into Control and IR groups. Insulin...
AimCardiac sympathetic afferent reflex (CSAR) participates in sympathetic over‐excitation. Superoxide anions and angiotensin II (Ang II) mechanisms are associated with sympathetic outflow and CSAR in the paraventricular nucleus (PVN). This study was designed to investigate whether PVN superoxide anions mediate CSAR and Ang II‐induced CSAR enhancement response in fructose‐induced insulin resistance...
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