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The characteristic dose profile of accelerated ions has opened up new horizons in the context of cancer treatment. However, particle range uncertainties strongly constrain the potentialities of ion beam therapy. In spite of worldwide efforts, a detector system for range and dose delivery assessment in real-time is not yet available for clinical routine.
In-beam SPECT during therapeutic proton beam irradiation is a novel method for three dimensional in-vivo dose verification. For this purpose a Compton camera design is evaluated with respect to the special requirements and conditions that arise from this application. Different concepts are studied by means of simulation concerning the angular resolution and efficiency. It was found that a cadmium...
The only clinically applied in-vivo dosimetry method for ion beams is Positron Emission Tomography (PET). Between 1997 and 2008, the in-beam PET method was used at the GSI Helmholtzzentrum für Schwerionenforschung, Darmstadt, Germany, for monitoring the dose delivered by 12C beams. Due to inherent limitations of this method, a direct quantification of the delivered dose is not feasible. Therefore,...
Positron emission tomography (PET) is a technique for an in-vivo, non-invasive monitoring of the dose delivery precision in highly conformal ion beam therapy. The successful exploitation of ion-beam PET and a rising number of built or planned proton and ion therapy facilities worldwide are working towards the development of a particle therapy PET (PT-PET) system of the next generation. Possible configurations...
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