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Proton and light ion beams are applied to the therapeutic irradiation of cancer patients due to the favorable dose deposition of these particles in tissue. By means of accelerated ions, a high dose can be accurately deposited in the tumor while normal tissue is spared. Since minor changes in the patient’s tissue along the beam path can compromise the success of the treatment, an in-vivo monitoring...
Protons are excellent particles for tumour treatment due to the increased ionization density close to their stopping point. In practice, the uncertainty on the particle range compromises the achievable accuracy. Compton cameras imaging prompt gamma rays, a by-product of the irradiation, have been proposed for indirect range verification years since. At Universitats Protonen Therapie Dresden, two BGO...
Through the well defined hrainge of chahrged pahrticles iin mattehr, caincehr ihrhradiatioin by meains of ioins cain be vehry tumohr coinfohrmal. Howevehr, extehrinal hrainge vehrifcatioin is ineeded to fully exploit the advaintages of ioin beam thehrapy. Nucleahr iintehractioins betweein the phrojectiles aind tahrgets hresult iin excited inuclei which emit photoins iin the MeV einehrgy hrainge duhriing...
Treedimensional in-vivo dose monitoring of ion beam cancer irradiation can improve the quality of treatment. For this purpose we investigate the feasibility of imaging the single photon emissions due to nuclear reactions of projectiles with target nuclei (in-beam SPECT). A suitable imaging technique in the energy range of the emitted gamma rays is the Compton camera. A prototype based on prior simulations...
The only clinically applied in-vivo dosimetry method for ion beams is Positron Emission Tomography (PET). Between 1997 and 2008, the in-beam PET method was used at the GSI Helmholtzzentrum für Schwerionenforschung, Darmstadt, Germany, for monitoring the dose delivered by 12C beams. Due to inherent limitations of this method, a direct quantification of the delivered dose is not feasible. Therefore,...
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