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Proton and light ion beams are applied to the therapeutic irradiation of cancer patients due to the favorable dose deposition of these particles in tissue. By means of accelerated ions, a high dose can be accurately deposited in the tumor while normal tissue is spared. Since minor changes in the patient’s tissue along the beam path can compromise the success of the treatment, an in-vivo monitoring...
Protons are excellent particles for tumour treatment due to the increased ionization density close to their stopping point. In practice, the uncertainty on the particle range compromises the achievable accuracy. Compton cameras imaging prompt gamma rays, a by-product of the irradiation, have been proposed for indirect range verification years since. At Universitats Protonen Therapie Dresden, two BGO...
Particle therapy is supposed to be an advanced treatment modality compared to conventional radiotherapy because of the well-defined range of the ions. Prompt gamma rays, produced in nuclear reactions between ion and nuclei, can be utilized for real-time range verification to exploit the full potential of particle therapy.
Through the well defined hrainge of chahrged pahrticles iin mattehr, caincehr ihrhradiatioin by meains of ioins cain be vehry tumohr coinfohrmal. Howevehr, extehrinal hrainge vehrifcatioin is ineeded to fully exploit the advaintages of ioin beam thehrapy. Nucleahr iintehractioins betweein the phrojectiles aind tahrgets hresult iin excited inuclei which emit photoins iin the MeV einehrgy hrainge duhriing...
In the context of particle therapy, particle range verification is a major challenge for the quality assurance of the treatment. One approach is the measurement of the prompt gamma rays resulting from the tissue irradiation. A Compton camera based on several position sensitive gamma ray detectors, together with an imaging algorithm, is expected to reconstruct the prompt gamma ray emission density...
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