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Sortases are cell‐membrane‐anchored cysteine transpeptidases that are essential for the assembly and anchoring of cell‐surface adhesins in Gram‐positive bacteria. Thus, they play critical roles in virulence, infection and colonization by pathogens. Sortases have been classified into four types based on their primary sequence and the target‐protein motifs that they recognize. All Gram‐positive bacteria...
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