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Currently, neurocysticercosis treatment involves two drugs: albendazole and praziquantel; however, their efficacy is suboptimal and new cysticidal drugs are needed. The present paper reports the cysticidal activity of extracts of the bark from Prunus serotina against Taenia crassiceps cysts and the isolation and identification of the main components of the most active extract. Results showed that...
The effect of two water-soluble polymers: pectin and polyvinylpyrrolidone in combination with β-cyclodextrin, on the dissolution, bioavailability and cysticidal efficacy of albendazole was evaluated using a commercial suspension as reference product. The dissolution of the albendazole–β-cyclodextrin–pectin formulation was slow and incomplete (44.7%). No statistical differences in C max and...
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