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Background
The current approach to manufacture cold‐stored platelets (CSP) replicates that of room temperature–stored platelets (RSP). However, this production method is associated with aggregate formation in CSP, a major pitfall that leads to significant wastage. We hypothesized that isolating platelets from whole blood as platelet‐rich plasma (PRP) and storing them at a lower concentration reduces...
BACKGROUND
Activation and consumption of platelets (PLT) and clotting factors along with hemolysis occurs when blood contacts the extracorporeal life support (ECLS) circuit and its components.
STUDY DESIGN AND METHODS
The objective was to examine the effects of reducing ECLS circuit volume by decreasing tubing length and changing components on blood product usage in neonatal and pediatric patients...
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