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Glutamate (Glu) and glutamine (Gln) play an important role in neuronal regulation and are of value as MRS‐observable diagnostic biomarkers. In this study the relative concentrations of these metabolites have been measured in multiple regions in the normal brain using a short‐TE whole‐brain MRSI measurement at 3 T combined with a modified data analysis approach that used spatial averaging to obtain...
Purpose
A feasibility study of an echo‐planar spectroscopic imaging (EPSI) using a short echo time (TE) that trades off sensitivity, compared with other short‐TE methods, to achieve whole brain coverage using inversion recovery and spatial oversampling to control lipid bleeding.
Methods
Twenty subjects were scanned to examine intersubject variance. One subject was scanned five times to examine...
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