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Background
Progressive supranuclear palsy (PSP) is an atypical Parkinsonian syndrome characterized by supranuclear gaze palsy, early postural instability, and a frontal dysexecutive syndrome. Contrary to normal brain magnetic resonance imaging in Parkinson's disease (PD), PSP shows specific cerebral atrophy patterns and alterations, but these findings are not present in every patient, and it is still...
Purpose
At ultra‐high field (UHF), B1+‐inhomogeneities and high specific absorption rate (SAR) of adiabatic slice‐selective RF‐pulses make spatial resolved spectral‐editing extremely challenging with the conventional MEGA‐approach. The purpose of the study was to develop a whole‐brain resolved spectral‐editing MRSI at UHF (UHF, B0 ≥ 7T) within clinical acceptable measurement‐time and minimal chemical‐shift‐displacement‐artifacts...