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Radiotracers such as 11 C-PiB have enabled the in vivo imaging of amyloid-β plaques in the brain, one of the histopathologic hallmarks of Alzheimer's disease (AD). Standardized uptake value ratio (SUVR) has become the most common normalization for 11 C-PiB as it does not require dynamic scans or blood sampling. Normalization is performed by computing the ratio of 11 C-PiB retention...
The segmentation of textured anatomy from magnetic resonance images (MRI) is a difficult problem. We present an approach that uses features extracted from the magnitude and phase of the MRI signal to segment the bones in the knee. Moreover, we show that by incorporating shape information, more accurate and anatomically valid segmentations are obtained.Eighteen volunteers were scanned in a whole-body...
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