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β-amyloid (Aβ) deposition is one of the neuropathological hallmarks of Alzheimer's disease (AD), Aβ burden can be quantified using 11 C PiB PET. Neuropathological studies have shown that the initial plaques are located in the temporal and orbitofrontal cortices, extending later to the cingulate, frontal and parietal cortices (Braak and Braak, 1997). Previous studies have shown an overlap in...
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