Search results for: Rotem S. Lanzman

Items from 1 to 20 out of 21 results

article

J‐difference‐edited MRS measures of γ‐aminobutyric acid before and after acute caffeine administration

Georg Oeltzschner, Helge J. Zöllner, Marc Jonuscheit, Rotem S. Lanzman, more

Magnetic Resonance in Medicine > 80 > 6 > 2356 - 2365

Purpose The aim of this study was to investigate potential effects of acute caffeine intake on J‐difference‐edited MRS measures of the primary inhibitory neurotransmitter γ‐aminobutyric acid (GABA). Methods J‐difference‐edited Mescher‐Garwood PRESS (MEGA‐PRESS) and conventional PRESS data were acquired at 3T from voxels in the anterior cingulate and occipital area of the brain in 15 healthy subjects,...

article

Functional MRI in transplanted kidneys

Alexandra Ljimani, Hans-Jörg Wittsack, Rotem S. Lanzman

Abdominal Radiology > 2018 > 43 > 10 > 2615-2624

Renal transplantation is the therapy of choice for patients with end-stage renal diseases. Improvement of immunosuppressive therapy has significantly increased the half-life of renal allografts over the past decade. Nevertheless, complications can still arise. An early detection of allograft dysfunction is mandatory for a good outcome. New advances in magnetic resonance imaging (MRI) have enabled...

article

Non‐gaussian diffusion evaluation of the human kidney by Padé exponent model

Alexandra Ljimani, Rotem S. Lanzman, Anja Müller‐Lutz, Gerald Antoch, more

Journal of Magnetic Resonance Imaging > 47 > 1 > 160 - 167

Purpose To evaluate the feasibility of renal diffusion quantification using the Padé exponent model (PEM) in healthy subjects. Materials and Methods Diffusion measurements were completed in 10 healthy subjects (mean age, 32.4 ± 8.9 years) on a 3T MRI scanner (Magnetom Trio, Siemens AG, Germany). A respiratory‐triggered echo planar imaging sequence (15 slices with 6 mm thickness; 16 b‐values [0–750...

article

CT angiography of the aorta using 80 kVp in combination with sinogram‐affirmed iterative reconstruction and automated tube current modulation: Effects on image quality and radiation dose

Johannes Boos, Joel Aissa, Rotem S Lanzman, Philipp Heusch, more

Journal of Medical Imaging and Radiation Oncology > 60 > 2 > 187 - 193

IntroductionThe objective of this study was to evaluate image quality and radiation dose of a CT angiography (CTA) protocol using 80 kVp in combination with iterative reconstruction and automated tube current modulation. MethodsNinety‐five aortic CTA examinations were included in this study. A novel 80 kVp aortic CTA‐protocol with iterative reconstruction was introduced in our department in March...

article

Age‐dependency of glycosaminoglycan content in lumbar discs: A 3t gagcEST study

Anja Müller‐Lutz, Christoph Schleich, Gael Pentang, Benjamin Schmitt, more

Journal of Magnetic Resonance Imaging > 42 > 6 > 1517 - 1523

PurposeTo analyze age‐dependency of glycosaminoglycan content using gagCEST (glycosaminoglycan chemical exchange saturation transfer) imaging in lumbar intervertebral discs of healthy volunteers. Materials and MethodsIn all, 70 volunteers without low back pain (mean age 44 ± 14 years, range: 21–69 years) were examined with T₂‐weighted and gagCEST imaging with a 3T MR scanner, with approval of the...

article

Functional evaluation of transplanted kidneys using arterial spin labeling MRI

Philipp Heusch, Hans‐Jörg Wittsack, Dirk Blondin, Alexandra Ljimani, more

Journal of Magnetic Resonance Imaging > 40 > 1 > 84 - 89

PurposeTo investigate non–contrast‐enhanced arterial spin labeling (ASL) MRI for functional assessment of transplanted kidneys at 1.5 Tesla (T) and 3T. Materials and MethodsThis study was approved by the local ethics committee, and written informed consent was obtained from all participants. Ninety eight renal allograft recipients (mean age, 51.5 ± 14.6 years) were prospectively included in this...

article

Pilot study of Iopamidol-based quantitative pH imaging on a clinical 3T MR scanner

Anja Müller-Lutz, Nadia Khalil, Benjamin Schmitt, Vladimir Jellus, more

Magnetic Resonance Materials in Physics, Biology and Medicine > 2014 > 27 > 6 > 477-485

Objective The objective of this study was to show the feasibility to perform Iopamidol-based pH imaging via clinical 3T magnetic resonance imaging (MRI) using chemical exchange saturation transfer (CEST) imaging with pulse train presaturation. Materials and methods The pulse train presaturation scheme of a CEST sequence was investigated for Iopamidol-based pH measurements using a 3T magnetic resonance...

article

Evaluation of the impact of organ-specific dose reduction on image quality in pediatric chest computed tomography

Johannes Boos, Patric Kröpil, Dirk Klee, Philipp Heusch, more

Pediatric Radiology > 2014 > 44 > 9 > 1065-1069

Background Organ-specific dose reduction significantly reduces the radiation exposure of radiosensitive organs. Objective The purpose of this study was to assess the impact of a novel organ-specific dose reduction algorithm on image quality of pediatric chest CT. Materials and methods We included 28 children (mean age 10.9 ± 4.8 years, range 3–18 years) who had contrast-enhanced chest CT on a...

article

Hybrid [18F]-FDG PET/MRI including non-Gaussian diffusion-weighted imaging (DWI): Preliminary results in non-small cell lung cancer (NSCLC)

Philipp Heusch, Jens Köhler, Hans-Joerg Wittsack, Till A. Heusner, more

European Journal of Radiology > 2013 > 82 > 11 > 2055-2060

To assess the feasibility of non-Gaussian DWI as part of a FDG-PET/MRI protocol in patients with histologically proven non-small cell lung cancer.15 consecutive patients with histologically proven NSCLC (mean age 61±11 years) were included in this study and underwent whole-body FDG-PET/MRI following whole-body FDG-PET/CT. As part of the whole-body FDG-PET/MRI protocol, an EPI-sequence with 5 b-values...

article

Does positron emission tomography data acquisition impact simultaneous diffusion-weighted imaging in a whole-body PET/MRI system?

Christian Buchbender, Verena Hartung-Knemeyer, Philipp Heusch, Till A. Heusner, more

European Journal of Radiology > 2013 > 82 > 2 > 380-384

The purpose of this study was to test whether the acquisition of positron emission tomography (PET) does interfere with simultaneous diffusion weighted imaging (DWI) in an integrated whole-body PET/MRI system.Fourteen consecutive oncological patients (9 men, 5 women; age 54±13 years ([mean±standard deviation]) scheduled for routine [ ¹⁸ F]-FDG PET/CT were prospectively enrolled. For DWI, an...

article

Impact of blood flow on diffusion coefficients of the human kidney: A time‐resolved ECG‐triggered diffusion‐tensor imaging (DTI) study at 3T

Philipp Heusch, Hans‐Jörg Wittsack, Patric Kröpil, Dirk Blondin, more

Journal of Magnetic Resonance Imaging > 37 > 1 > 233 - 236

Purpose:To evaluate the impact of renal blood flow on apparent diffusion coefficients (ADC) and fractional anisotropy (FA) using time‐resolved electrocardiogram (ECG)‐triggered diffusion‐tensor imaging (DTI) of the human kidneys. Materials and Methods:DTI was performed in eight healthy volunteers (mean age 29.1 ± 3.2) using a single slice coronal echoplanar imaging (EPI) sequence (3 b‐values: 0,...

article

Cone Beam CT in Assessment of Tibial Bone Defect Healing: An Animal Study

Patric Kröpil, Ahmad R. Hakimi, Pascal Jungbluth, Carolin Riegger, more

Academic Radiology > 2012 > 19 > 3 > 320-325

To evaluate cone beam computed tomography (CBCT) for monitoring of tibial bone defect healing in comparison to histopathological findings.Circumscribed tibial bone defects were created in 16 mini-pigs and imaging of the tibia was performed on day 42 using a modern CBCT scanner with flat panel detector (PaX-Duo3D, Vatech, Korea). The extent of osseous consolidation including remaining calcium phosphate...

article

Co-operative Learning In Clinical Radiology (CLICR): Vorstellung eines neuen Lehrkonzepts für die Radiologie im Kontext eines kompetenzorientierten Curriculums

Axel Scherer, Patric Kröpil, Philipp Heusch, Philipp Sewerin, more

Zeitschrift fuer Evidenz, Fortbildung und Qualitaet im Gesundheitswesen > 2012 > 106 > 1 > 54-61

Medizinische Curricula unterliegen derzeit einem Reformprozess mit einer Hinwendung zu interaktiven, fallbasierten Lehrkonzepten. In diesem Beitrag wird eine neuartige radiologische Lehrveranstaltung (CLICR-Kurs), die verschiedene innovative Ausbildungselemente vereint, beschrieben und erste Erfahrungen bei der praktischen Umsetzung sowie Evaluationsergebnisse vorgestellt.Es wurde ein neues Kursangebot...

article

Quantitative assessment of bone defect healing by multidetector CT in a pig model

Carolin Riegger, Patric Kröpil, Pascal Jungbluth, Rotem S. Lanzman, more

Skeletal Radiology > 2012 > 41 > 5 > 531-537

Objective To evaluate multidetector CT volumetry in the assessment of bone defect healing in comparison to histopathological findings in an animal model. Materials and methods In 16 mini-pigs, a circumscribed tibial bone defect was created. Multidetector CT (MDCT) of the tibia was performed on a 64-row scanner 42 days after the operation. The extent of bone healing was estimated quantitatively by...

article

Cartilage quality in rheumatoid arthritis: comparison of T2* mapping, native T1 mapping, dGEMRIC, ΔR1 and value of pre-contrast imaging

Christian Buchbender, Axel Scherer, Patric Kröpil, Birthe Körbl, more

Skeletal Radiology > 2012 > 41 > 6 > 685-692

Purpose To prospectively evaluate four non-invasive markers of cartilage quality—T2* mapping, native T1 mapping, dGEMRIC and ΔR1—in healthy volunteers and rheumatoid arthritis (RA) patients. Materials and methods Cartilage of metacarpophalangeal (MCP) joints II were imaged in 28 consecutive subjects: 12 healthy volunteers [9 women, mean (SD) age 52.67 (9.75) years, range 30–66] and 16 RA patients...

article

Motion correction improves image quality of dGEMRIC in finger joints

Falk Miese, Patric Kröpil, Benedikt Ostendorf, Axel Scherer, more

European Journal of Radiology > 2011 > 80 > 3 > e427-e431

To assess motion artifacts in dGEMRIC of finger joints and to evaluate the effectiveness of motion correction.In 40 subjects (26 patients with finger arthritis and 14 healthy volunteers) dGEMRIC of metacarpophalangeal joint II was performed. Imaging used a dual flip angle approach (TE 3.72ms, TR 15ms, flip angles 5° and 26°). Two sets of T1 maps were calculated for dGEMRIC analysis from the imaging...

article

Delayed gadolinium‐enhanced MRI of cartilage (dGEMRIC) and morphologic MRI of cartilage in the long‐term follow‐up after Legg–Calvé–Perthes disease (LCPD)

Arne Holstein, Christoph Zilkens, Bernd Bittersohl, Marcus Jäger, more

Journal of Medical Imaging and Radiation Oncology > 55 > 3 > 259 - 265

Introduction: The purpose of the present study was to evaluate the feasibility of delayed gadolinium‐enhanced magnetic resonance imaging of cartilage (dGEMRIC) in the detection of cartilage changes versus morphologic imaging in the long‐term course of Legg–Calvé–Perthes disease (LCPD). Methods: A total of 31 hips in 26 patients (mean age, 30.0 years; range, 18–54 years) who were diagnosed with LCPD...

article

Minimally Invasive Catheter Procedures to Assist Complicated Pacemaker Lead Extraction and Implantation in the Operating Room

Patric Kröpil, Rotem S. Lanzman, Falk R. Miese, Dirk Blondin, more

CardioVascular and Interventional Radiology > 2011 > 34 > 2 > 345-351

We report on percutaneous catheter procedures in the operating room (OR) to assist complicated manual extraction or insertion of pacemaker (PM) and implantable cardioverter defibrillator leads. We retrospectively reviewed complicated PM revisions and implantations performed between 2004 and 2009 that required percutaneous catheter procedures performed in the OR. The type of interventional procedure,...

article

Hybrid ¹⁸F-FDG PET–MRI of the hand in rheumatoid arthritis: initial results

Falk Miese, Axel Scherer, Benedikt Ostendorf, Alexander Heinzel, more

Clinical Rheumatology > 2011 > 30 > 9 > 1247-1250

18F-fluorodeoxyglucose PET (18F-FDG PET) is highly sensitive to inflammatory changes within the synovial tissue in rheumatoid arthritis (RA). However, the highest spatial resolution for soft tissue can be achieved with MRI. Here, we report on the first true hybrid PET–MRI examination of the hand in early RA exploiting the advantages of both modalities. PET–MRI was performed with a prototype of an...

article

Statistical evaluation of diffusion‐weighted imaging of the human kidney

Hans‐Jörg Wittsack, Rotem S. Lanzman, Christian Mathys, Hendrik Janssen, more

Magnetic Resonance in Medicine > 64 > 2 > 616 - 622

The signal of diffusion‐weighted imaging of the human kidney differs from the signal in brain examinations due to the different microscopic structure of the tissue. In the kidney, the deviation of the signal behavior of monoexponential characteristics is pronounced. The aim of the study was to analyze whether a mono‐ or biexponential or a distribution function model fits best to describe diffusion...

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Search results for: Rotem S. Lanzman

J‐difference‐edited MRS measures of γ‐aminobutyric acid before and after acute caffeine administration

Functional MRI in transplanted kidneys

Non‐gaussian diffusion evaluation of the human kidney by Padé exponent model

CT angiography of the aorta using 80 kVp in combination with sinogram‐affirmed iterative reconstruction and automated tube current modulation: Effects on image quality and radiation dose

Age‐dependency of glycosaminoglycan content in lumbar discs: A 3t gagcEST study

Functional evaluation of transplanted kidneys using arterial spin labeling MRI

Pilot study of Iopamidol-based quantitative pH imaging on a clinical 3T MR scanner

Evaluation of the impact of organ-specific dose reduction on image quality in pediatric chest computed tomography

Hybrid [18F]-FDG PET/MRI including non-Gaussian diffusion-weighted imaging (DWI): Preliminary results in non-small cell lung cancer (NSCLC)

Does positron emission tomography data acquisition impact simultaneous diffusion-weighted imaging in a whole-body PET/MRI system?

Impact of blood flow on diffusion coefficients of the human kidney: A time‐resolved ECG‐triggered diffusion‐tensor imaging (DTI) study at 3T

Cone Beam CT in Assessment of Tibial Bone Defect Healing: An Animal Study

Co-operative Learning In Clinical Radiology (CLICR): Vorstellung eines neuen Lehrkonzepts für die Radiologie im Kontext eines kompetenzorientierten Curriculums

Quantitative assessment of bone defect healing by multidetector CT in a pig model

Cartilage quality in rheumatoid arthritis: comparison of T2* mapping, native T1 mapping, dGEMRIC, ΔR1 and value of pre-contrast imaging

Motion correction improves image quality of dGEMRIC in finger joints

Delayed gadolinium‐enhanced MRI of cartilage (dGEMRIC) and morphologic MRI of cartilage in the long‐term follow‐up after Legg–Calvé–Perthes disease (LCPD)

Minimally Invasive Catheter Procedures to Assist Complicated Pacemaker Lead Extraction and Implantation in the Operating Room

Hybrid ¹⁸F-FDG PET–MRI of the hand in rheumatoid arthritis: initial results

Statistical evaluation of diffusion‐weighted imaging of the human kidney

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