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The methylation reaction of arsenic trioxide conducted at 37°C and pH 7.0 for 24h using hydrophobic methylated vitamin B 12 , (methyl) (aquo) heptamethylcobyrinate perchlorate, CH 3 B 12 ester, as a methyl donor in the presence of reduced glutathione (GSH) yielded monomethylarsonous acid (MMA), dimethylarsinic acid (DMA), and trimethylarsine oxide (TMAO) as products with a...
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