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Ipilimumab is a human anti‐CTLA‐4 monoclonal antibody recently approved for the treatment of advanced melanoma. Stimulation of T‐cell activity unmasks antitumor activity, but can cause immune‐related adverse events. Autoimmune hypophysitis is of particular importance because its presentation can be subtle but life threatening. We present two cases where early recognition of ipilimumab‐related autoimmune...
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