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The purpose of this study was to develop a new biodegradable bone substitute materials consisting of synthesized hydroxyapatite (HAp) and Type I biodegradable honeycomb collagen sponge (HCS) composites. Apatite-coated Honeycomb collagen composite scaffolds (HAp-HCS) was fabricated and the proliferation and differentiation of MC 3T3-E1 cells were examined for the assessment of their biocompatibility...
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