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In the fly, thorough retinoid deprivation is possible, to optimize investigation of the effects of vitamin A metabolites and retinoic acid (RA) on visual development. Retinoids had been found to control fly opsin gene transcription, though this finding was contested. Northern blots onDrosophilaheads showed that mRNA of Rh1 (the predominant rhodopsin) was high in vitamin A replete controls, very low...
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