The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
Efficient cell internalization of framework nucleic acid nanostructures free of transfection agents provides new opportunities for developing biocompatible and intelligent nanoprobes and drug delivery carriers. Here, a proteomic identification method to screen target proteins that interact with tetrahedral DNA nanostructures (TDNs) during the process of endocytosis by combining drug affinity responsive...
Terahertz (THz) biological imaging has attracted intense attention due to its capability of acquiring physicochemical information in a label‐free, noninvasive, and nonionizing manner. However, extending THz imaging to the single‐molecule level remains a challenge, partly due to the weak THz reflectivity of biomolecules with low dielectric constants. Here, the development of graphene‐mediated THz scattering‐type...
In article number 2005814, Jiang Li, Huabin Wang, and co‐workers demonstrate the imaging of single protein molecules with a scattering‐type terahertz (THz) scanning near‐field optical microscope, taking advantage of a graphene substrate with high THz reflectivity and atomic smoothness, and a long platinum probe with high scattering ability. This strategy opens new routes to imaging single biomolecules...
Effective drug delivery systems that can systematically and selectively transport payloads to disease cells remain a challenge. Here, a targeting ligand‐modified DNA origami nanostructure (DON) as an antibody–drug conjugate (ADC)‐like carrier for targeted prostate cancer therapy is reported. Specifically, DON of six helical bundles is modified with a ligand 2‐[3‐(1,3‐dicarboxy propyl)‐ureido] pentanedioic...
In article number 1800613, Haosheng Chen and co‐workers fabricate highly uniform thick coatings encapsulating microspheres. Heavy microspheres loaded in a rolling emulsion droplet (density ratio of the microspheres to droplet over 5) driven by the continuous flow in a pipe can be lifted to the center of the droplet against gravity by the hydrodynamic force generated in the lubrication film circulating...
Forming uniform thick coatings on microspheres remains a significant challenge in various surface modification and drug delivery applications. In this work, a hydrodynamic method is demonstrated for centering microspheres in droplets with sizes ranging from tens to hundreds of micrometers. The core microspheres stay at the center of the droplets due to the hydrodynamic pressure generated in the surrounding...
Nanocasting, using ordered mesoporous silica or carbon as a hard template, has enormous potential for preparing novel mesoporous materials with new structures and compositions. Although a variety of mesoporous materials have been synthesized in recent years, the growth mechanism of nanostructures in a confined space, such as mesoporous channels, is not well understood, which hampers the controlled...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.