Search results for: Yilu Xu

Items from 1 to 11 out of 11 results

article

One amino acid drives the lipid droplet targeting sequence of a new noncoding RNA‐encoded protein to mitochondrion

Quan Yuan, Kaixuan Zheng, Ting Huang, Zelun Zhi, more

Over the past decade, the majority of the mammalian genome considered to be noncoding has been revealed to be able to produce proteins. Many RNA molecules, mis‐annotated as noncoding, actually are predicted to code for proteins. Some of those proteins have been identified and verified to play critical roles in multiple biological processes. The lipid droplet (LD) is a unique cellular organelle bound...

article

H₂O₂ induces PP2A demethylation to downregulate mTORC1 signaling in HEK293 cells

Shen Tang, Fu Qin, Xinhang Wang, Ziwei Liang, more

Cell Biology International > 42 > 9 > 1182 - 1191

Mammalian target of rapamycin (mTOR) is a Ser/Thr protein kinase that functions as an ATP and amino acid sensor to govern cell growth and proliferation by mediating mitogen‐ and nutrient‐dependent signal transduction. Protein phosphatase 2A (PP2A), a ubiquitously expressed serine/threonine phosphatase, negatively regulates mTOR signaling. Methylation of PP2A is catalyzed by leucine carboxyl methyltransferase‐1...

article

Involvement of gap junctions in astrocyte impairment induced by manganese exposure

Cailing Lu, Zhijuan Meng, Yiyuan He, Deqiang Xiao, more

Brain Research Bulletin > 2018 > 140 > C > 107-113

Glutamate excitotoxicity, characterized as excessive glutamate stress, is considered to be involved in cerebral ischaemia, brain trauma, and neurodegenerative diseases such as Parkinson’s disease and Alzheimer's disease. Glutamate homeostasis disruption was highlighted in Mn neurotoxicity caused by high levels of Mn. Astrocytes, accounting for approximately 50% of the neuronal cells in the central...

article

Biochar modulates heavy metal toxicity and improves microbial carbon use efficiency in soil

Yilu Xu, Balaji Seshadri, Binoy Sarkar, Hailong Wang, more

Science of The Total Environment > 2018 > 621 > C > 148-159

Soil organic carbon is essential to improve soil fertility and ecosystem functioning. Soil microorganisms contribute significantly to the carbon transformation and immobilisation processes. However, microorganisms are sensitive to environmental stresses such as heavy metals. Applying amendments, such as biochar, to contaminated soils can alleviate the metal toxicity and add carbon inputs. In this...

article

The potential value of biochar in the mitigation of gaseous emission of nitrogen

Ramya Thangarajan, Nanthi S. Bolan, Anitha Kunhikrishnan, Hasintha Wijesekara, more

Science of The Total Environment > 2018 > 612 > C > 257-268

Nitrogen (N) losses through gaseous emission of ammonia (NH₃) and nitrous oxide (N₂O) can contribute to both economic loss and environmental degradation. This study examined the effect of biochar and a chemical nitrification inhibitor, dicyandiamide (DCD), on N transformation and N losses via gaseous emission of NH₃ and N₂O from agricultural soils treated with a range of organic and inorganic N sources...

article

Immobilization of lead and copper in aqueous solution and soil using hydroxyapatite derived from flue gas desulphurization gypsum

Yang Liu, Yubo Yan, Balaji Seshadri, Fangjie Qi, more

Journal of Geochemical Exploration > 2018 > 184 > PB > 239-246

Flue gas desulphurization (FGD) gypsum is an abundant waste generated from coal-fired power plants. This study evaluated the potential application of hydroxyapatite (F-HAP) derived from FGD gypsum for immobilization of lead (Pb) and copper (Cu) in water and soil. MINTEQ software was employed to determine the species distribution of Pb(II) and Cu(II) at different solution pH conditions. The factors...

article

Response to the letter to editor “Cadmium exposure and urinary N-acetyl-β-D-glucosaminidase: a meta-analysis”

Cuixia Liu, Yubiao Li, Chunshui Zhu, Zhaomin Dong, more

Environmental Science and Pollution Research > 2017 > 24 > 12 > 11862- 11863

Responsible editor: Philippe Garrigues

article

A Computational Mechanistic Study of Metal‐Catalyzed Remote C–H Functionalizations – Insights into the Origin of Regioselectivity and the Role of Acid

Yilu Xu, Shengwen Yang, Lijuan Du, Juan Li

European Journal of Organic Chemistry > 2017 > 2 > 381 - 388

The metal‐catalyzed remote C–H functionalization of quinoline N‐oxide was investigated systematically through density functional theory calculations. We found that the coordination of the N‐oxide moiety to a metal center greatly lowered the barrier to C–H activation and made C8–H activation favorable, regardless of the metal center (Ir, Rh, or Pd). For Ir^III and Rh^III systems, the active catalyst...

article

Utilization of phosphorus loaded alkaline residue to immobilize lead in a shooting range soil

Yubo Yan, Fangjie Qi, Balaji Seshadri, Yilu Xu, more

Chemosphere > 2016 > 162 > C > 315-323

The alkaline residue generated from the production of soda ash using the ammonia-soda method has been successfully used in removing phosphorus (P) from aqueous solution. But the accumulation of P-containing solid after P removal is an undesirable menace to the environment. To achieve the goal of recycling, this study explored the feasibility of reusing the P loaded alkaline residue as an amendment...

article

Benchmark dose for cadmium exposure and elevated N-acetyl-β-d-glucosaminidase: a meta-analysis

CuiXia Liu, YuBiao Li, ChunShui Zhu, ZhaoMin Dong, more

Environmental Science and Pollution Research > 2016 > 23 > 20 > 20528- 20538

Cadmium (Cd) is a well-known nephrotoxic contaminant, and N-acetyl-β-d-glucosaminidase (NAG) is considered to be an early and sensitive marker of tubular dysfunction. The link between Cd exposure and NAG level enables us to derive the benchmark dose (BMD) of Cd. Although several reports have already documented urinary Cd (UCd)-NAG relationships and BMD estimations, high heterogeneities arise due to...

article

Co-composting solid biowastes with alkaline materials to enhance carbon stabilization and revegetation potential

Saikat Chowdhury, Nanthi S. Bolan, Balaji Seshadri, Anitha Kunhikrishnan, more

Environmental Science and Pollution Research > 2016 > 23 > 8 > 7099-7110

Co-composting biowastes such as manures and biosolids can be used to stabilize carbon (C) without impacting the quality of these biowastes. This study investigated the effect of co-composting biowastes with alkaline materials on C stabilization and monitored the fertilization and revegetation values of these co-composts. The stabilization of C in biowastes (poultry manure and biosolids) was examined...

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