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The predicted Exigobacterium sibiricum bacterirhodopsin gene was amplified from an ancient Siberian permafrost sample. The protein bacteriorhodopsin from Exiguobacterium sibiricum (ESR) encoded by this gene was expressed in Escherichia coli membrane. ESR bound all-trans-retinal and displayed an absorbance maximum at 534nm without dark adaptation. The ESR photocycle is characterized by fast formation...
Introduction: In spite of intensive study of pathogenesis of migraine, immune mechanisms of the disease remain unknown.Materials and Methods: NK cell activity against labelled with 3H-uridine human K562 erythromyeloblasts was studied in 40 patients with migraine (14 males and 26 females), 15 of whom received a short sumatriptan trial subcutaneously or in tablets, and in 36 healthy subjects (13 males...
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